Corporal Bower (Ben Foster) and Lieutenant Payton (Dennis Quaid) are unceremoniously awakened from their hypersleep aboard their ship the Elysium. Upon reacclimating themselves, they discover that the rest of the crew is missing but clearly signs of life are abound. Trying to reach the reactor to save the ship, Bower finds an abundance of horrific encounters - both human and non.
As Bower makes his way through the ship, he stumbles across the bodies of crew members, some alive, others dead. He makes acquaintances along the way who are valuable resources and help put some of the pieces of what's going on together and assist him in defending against any and all comers. Meanwhile, Payton finds another crew member who he feels is acting weird, when it's really the crew member who is explaining the symptoms of Pandorum which reflects some of the symptoms Payton is showcasing. There is a contentious relationship between the two resulting in the discovery that Payton is really Gallo, another corporal who killed Payton and other crew members.
I couldn't help but find some parallels between scenes here and from The Descent. The creatures themselves are somewhat reminiscent minus the Legion of Doom shoulder pads, make the same noises and there's even a scene where Bower and another character are in a pool of blood surrounded by skeletal remains.
~TJ